Marcelo Bravo, Chief Technology Officer at Oxford Pharmascience (LON:OXP), explains to Proactiveinvestors how the company re-engineers existing drugs to improve the way they work and overcome side effects. Marcelo discusses the recent successful study for ibuprofen and the launch of the safer NSAID programme, the news of which drove shares to two year highs.

Sandeep Jaitly, fund manager at First International, tells Proactiveinvestors that, at current exchange rates, he's overweight silver vs gold and fully expects the spread to narrow. He says that gold and silver streaming companies are looking very interesting and he mentions Silver Wheaton and Sandstorm Gold in particular.

Sam Spring, President and CEO of Kincora Copper (CVE:KCC), tells Proactiveinvestors that after putting in place a full re-examination of its work last year at Bronze Fox, it is now refining its exploration targets for this year. Sam also discusses the new remuneration structure for company directors.

Len Fertig, CEO of Motive Television (LON:MTV), tells Proactiveinvestors that the recent news with Freeview gives the company a big opportunity. Len also discusses where he sees the company spending the £500,000 that was recently raised.

Michael Pilsworth, Chairman of Motive Television (LON:MTV), talks through the presentation given to Proactive Investors on 16th May 2013.

John Aldersey-Williams, CEO of SeaEnergy (LON:SEA), tells Proactiveinvestors that the company now has three integrated businesses in marine, consulting and in offshore software services and support with R2S, the company it bought last year. John reckons R2S, which, he says, offers a type of 'Google Street View' for offshore installations, should prove popular with blue-chip international oil companies. John also says that the existing interests in the 'legacy' assets, like its 21% stake in Lansdowne Oil & Gas, are no longer core to the business and over time SeaEnergy will exit these and return a proportion of funds to shareholders.

Daniel Elger, CFO of e-Therapeutics (LON:ETX), tells Proactiveinvestors that the preliminary clinical tests on the ETS2101 cancer drug are progressing well and are on course to report key data around the end of the year. Daniel says anti-depressant drug ETS6103 is also moving on and patients are expected to be enrolled soon with a view to having that data by the second half of 2014.

Sandy Chim, President & CEO of Century Iron Mines (TSX:FER), tells Proactiveinvestors that the recent Preliminary Economic Assessment shows C$60mln of cashflow a year from the Joyce Lake project from 2015. Sandy also talks about the shares that the management team have been buying.

David Patterson, Chairman & Director of Donner Metals (CVE:DON), tells Proactiveinvestors that, as production starts at its first mine, the company sees 'tremendous opportunities'. Dave says that, with its expertise, it's in a good position to grow the company through merger and acquisition.

Angelos Damaskos, head of the Junior Gold Fund, talks to Proactive Investors about the tough times facing junior gold firms. With gold prices dipping below production prices for many, and access to new funds limited, Damaskos discusses which of the 'mining giants of tomorrow' are smart bets for investors.

William Howe, Managing Director of Metminco (LON:MNC ASX:MNC), tells Proactive Investors about his firm's plans for the Los Calatos copper project in Peru. He talks about recent results from a scoping study, as well as the search for a strategic partner to work with it on development of the site. Howe also addresses concerns about the company's capital position and explains why it is so important that Los Calatos has been designated 'a site of national interest'.

Mobile phone giant Vodafone hit the headlines today as it revealed worse trading in its third quarter due to pressures in Europe. LON:VOD, LON:TT., LON:TCG, LON:OBT, LON:GAS, LON:SOLG, LON:BGL, LON: SML

Royal Bank of Scotland is set to pile more pressure on the British banking sector today as it readies itself for a fine from regulators over Libor rigging. LON:RBS LON:SUMM LON:AAZ LON:VOG LON:MOG LON:FJT LON:HAWK LON:BARC LON:LOQ

Gold companies were eyeing up gains on Tuesday with plenty of news from the junior sector to get investors licking their lips, with Ariana Resources and Condor Gold featuring.

With South Africa's Indaba mining conference underway in Cape Town, all eyes are on the mining heavyweights at the start of the week

Shares in the telecoms giant rang up on the last day of the trading week as it managed to beat profit forecasts in the latest quarter

On a big day for the UK heavyweights, oil giant Shell and alcoholic drinks group Diageo dragged the UK's leading stocks lower after falling short of the City's best guesses.

Cigarette maker IMPs was a huge drag on the Footsie as it reported that black market sales are proving a real problem in the European Union.

The mining giant is to take a $4bn hit on its Minas-Rio iron ore project in Brazil as spending has had to be increased for a sixth time at the mine

Budget carriers Ryanair and easyJet shares slipped in early play. The former's decline came in the face of increased profit expectations, while the latter saw shares dip in the wake of its...

8/2/12 Ian Bowles, CEO of Allocate Software (LON:ALL), tells Proactiveinvestors that with good institutional support the value proposition is very compelling with the stock at 79p. He says that while he is now looking overseas for opportunities there still remains a significant opportunity for Allocate Software in its primary business here in the UK healthcare market; with 42% of the sector already using Allocate's programming, there remains 39% of the NHS still not using ANY rostering software.